重组小鼠胶质细胞谷氨酸运载蛋白2
英文名称 | Recombinant mouse EAAT2 protein, GST & His |
中文名称 | 重组小鼠胶质细胞谷氨酸运载蛋白2 |
别 名 | EAAT2; Excitatory amino acid transporter 2; Excitotoxic amino acid transporter 2; Glial high affinity glutamate transporter; GLT 1; GLT1; Glutamate aspartate transporter II; SLC1A2; Sodium dependent glutamate aspartate transporter 2; Solute carrier family 1 glial high affinity glutamate transporter member 2; Solute carrier family 1 member 2; Excitatory amino acid transporter 2; GLT-1; SLC1A2; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2; Recombinant mouse EAAT2 protein, GST & His |
理论分子量 | 40kDa |
检测分子量 | 42 kDa |
性 状 | Lyophilized or Liquid |
浓 度 | >0.5 mg/ml |
物 种 | Mouse |
序 列 | 460-572/572 |
纯 度 | >95% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | E.coli |
活性 | Not tested |
标签 | GST & His |
缓 冲 液 | 20 mM Tris-HCl (pH=8.0) |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010] |