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Trimethobenzamide hydrochloride
CAS No. : 554-92-7
MCE 国际站：Trimethobenzamide hydrochloride
产品活性：Trimethobenzamide hydrochloride 是多巴胺 D2 受体阻断剂，可用作预防恶心和呕吐的止吐剂。
研究领域：GPCR/G Protein | Neuronal Signaling | Anti-infection
作用靶点：Dopamine Receptor | Influenza Virus
In Vitro: Trimethobenzamide is a (non-phenothiazine) benzamide antiemetic that acts centrally to block D2 receptors, thereby inhibiting the medullary chemoreceptor trigger zone by blocking emetic impulses to the vomiting center.
In Vivo: The oral bioavailability of Trimethobenzamide is 60% to 100%. The time to peak is about 45 minutes after oral administration and; Intramuscular (I.M.) administration about 30 minutes after intramuscular administration.
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