| 产品编号 |
YB-9006R-FITC |
| 英文名称 |
Anti-CECR6/FITC |
| 中文名称 |
FITC标记的猫眼综合征染色体候选基因6抗体 |
| 别 名 |
Cat eye syndrome chromosome region candidate 6; Cat eye syndrome chromosome region candidate 6 homolog (human); Cat eye syndrome chromosome region candidate 6 homolog; RGD1565302; AW048664; CECR6_HUMAN. |
| 规格价格 |
100ul/2980元 购买 大包装/询价 |
| 说 明 书 |
100ul |
| 研究领域 |
细胞生物 免疫学 |
| 抗体来源 |
Rabbit |
| 克隆类型 |
Polyclonal |
| 交叉反应 |
Human, Mouse, Rat, Dog, Cow, Sheep, |
| 产品应用 |
IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
58kDa |
| 性 状 |
Lyophilized or Liquid |
| 浓 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human CECR6 |
| 亚 型 |
IgG |
| 纯化方法 |
affinity purified by Protein A |
| 储 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 |
background:
Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.
Tissue Specificity:
Widely expressed, especially in adult heart, brain, prostate, testes, peripherical blood leukocytes and fetal brain.
Database links:
Entrez Gene: 27439 Human
Entrez Gene: 94047 Mouse
SwissProt: Q9BXQ6 Human
SwissProt: Q99MX7 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
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