FITC标记的卷曲螺旋结构域蛋白8抗体
产品名称： FITC标记的卷曲螺旋结构域蛋白8抗体
英文名称： Anti-CCDC8/FITC
产品编号： HZ-8138R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-CCDC8/FITC Conjugated antibody
FITC标记的卷曲螺旋结构域蛋白8抗体
| 英文名称 | Anti-CCDC8/FITC |
| 中文名称 | FITC标记的卷曲螺旋结构域蛋白8抗体 |
| 别 名 | CCDC8; CCDC8_HUMAN; Coiled-coil domain-containing protein 8; DKFZp564K0322; ENSMUSG00000041117; MGC72567. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 免疫学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Dog, Pig, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 59kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CCDC8 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011]. Subunit: Interacts with OBSL1. Tissue Specificity: Widely expressed with low levels in spleen, skeletal muscle, small intestine, kidney and liver. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. DISEASE: Defects in CCDC8 are the cause of 3M syndrome type 3 (3M3) [MIM:614205]. A disorder characterized by poor postnatal growth and distinctive facial features, including triangular facies, frontal bossing, fleshy tipped nose, and fleshy lips. Other features may include skeletal anomalies and prominent heels. Database links: UniProtKB/Swiss-Prot: Q9H0W5.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因编码含有卷曲螺旋结构域的蛋白质。编码的蛋白质作为p53介导的DNA损伤后的细胞凋亡的辅助因子，也可能通过与细胞骨架适配器蛋白-朦胧素样1的相互作用在生长中发挥作用。这种基因突变是3M症候群-3（3m3）的一个原因。[ RefSeq，DEC 2011 ]提供。