BCL11A 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
BCL11A 抗体

BCL11A 抗体

商家询价

产品名称： BCL11A 抗体

英文名称： BCL11A Antibody

产品编号： XY11613-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 BCL11A 抗体

Applications
In-house applications ELISA, IHC     Application not tested? Please see our Guarantee.
Species specificity Human, mouse, rat; other species not tested.
Images
Prev1NextView more validation data
  • 11613-1-AP;GliomasImmunohistochemical of paraffin-embedded human gliomas using 11613-1-AP(BCL11A antibody) at dilution of 1:50 (under 10x lens)
Positive IHC detected in Human gliomas
Recommended dilution IHC : 1:20-1:200
BCL11A 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen BCL11A fusion protein ag2187 Full name B-cell CLL/lymphoma 11A (zinc finger protein)
Calculated molecular
weight		 835aa,91 kDa Observed molecular 
weight		  
GenBank accession 
number		 BC021098 Gene ID (NCBI) 53335
Gene symbol BCL11A Synonyms BCL11A, HBFQTL5, CTIP1, FLJ34997, KIAA1809
BackgroundBCL11A 抗体

B-CELL CLL/LYMPHOMA 11A(BCL11A)is a highly conserved zinc finger gene. It acts as a myeloid and B-cell proto-oncogene, and may play key roles in leukemogenesis and hematopoiesis. It is an essential factor in lymphopoiesis, and required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1. It is also involved in lymphoid malignancies through translocation or amplification events. It has recently been shown that BCL11A expression is inversely correlated with γ globin expression.(PMID:21156846). This is a rabbit polyclonal antibody raised against part chain of N-terminal BCL11A of human origin. There are three isoforms of BCL11A: isoform1(773aa), isoform2(486aa) and isoform3(239aa)BCL11A 抗体

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