HS1BP3,造血干细胞特异性相关结合蛋白3抗体

产品编号HZ-11568R
英文名称HS1BP3
中文名称造血干细胞特异性相关结合蛋白3抗体
别 名ETM2; FLJ14249; H1BP3_HUMAN; HCLS1 binding protein 3; HCLS1-binding protein 3; HS1 binding protein 3; HS1 BP3; HS1-BP3; HS1-binding protein 3; Hs1bp3; HSP1BP-3.
说 明 书0.1ml 0.2ml
研究领域细胞生物 神经生物学 信号转导 干细胞
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
HS1BP3,造血干细胞特异性相关结合蛋白3抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量43kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human HS1BP3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
HS1BP3,造血干细胞特异性相关结合蛋白3抗体PubMedPubMed
产品介绍background:
HS1BP3 is a 392 amino acid protein that contains one PX (phox homology) domain, a leucine zipper, immunoreceptor tyrosine-based inhibitory motif-like motifs and multiple proline-rich regions. Expressed primarily in brain, HS1BP3 is encoded by a gene mapping to human chromosome 2p24.1. The gene encoding HS1BP3 is frequently mutated in familial essential tremor, a disorder characterized by kinetic tremor the the hands, voice or head, though there is no correlation to Parkinson disease. HS1BP3 interacts with HAX-1’s SH3 domain, and may also play a role in the regulation of catecholamine and serotonin metabolism. Acting as a regulator of IL-2 signaling, HS1BP3 is likely involved in lymphocyte activation.

Function:
May be a modulator of IL-2 signaling.

Subunit:
Binds HCLS1. Interacts with the SH3 domain of HCLS1 in vitro

Similarity:
Contains 1 PX (phox homology) domain.

Database links:
UniProtKB/Swiss-Prot: Q53T59.1

HS1BP3,造血干细胞特异性相关结合蛋白3抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.