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上海信裕生物科技有限公司
DOK5抗体

DOK5抗体

商家询价

产品名称： DOK5抗体

英文名称： DOK5Antibody

产品编号： XY11948-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 DOK5抗体

Applications
In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 11948-1-AP;mouse liver tissuemouse liver tissue were subjected to SDS PAGE followed by western blot with 11948-1-AP(DOK5 antibody) at dilution of 1:300
Positive WB detected in Mouse liver tissue
Recommended dilution WB : 1:500-1:5000
 DOK5抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information DOK5抗体
Immunogen DOK5 fusion protein ag2615 Full name Docking protein 5
Calculated molecular
weight		 306aa,35 kDa Observed molecular 
weight		 35kd
GenBank accession 
number		 BC008992 Gene ID (NCBI) 55816
Gene symbol DOK5 Synonyms C20orf180, docking protein 5, DOK5, Insulin receptor substrate 6, IRS 6, IRS6
Background

DOK5 belongs to the docking family of proteins that contain tandem pleckstrin homology-phosphotyrosine binding (PH-PTB) domains at their amino termini (PMID: 19909370). DOK proteins are also known as insulin receptor substrates (IRS) and serve as substrates for insulin and insulin-like growth factor (PMID: 12730241 ) as well as various protein tyrosine kinases (PMID: 16647839). DOK5 functions as a specific signal transduction molecule and plays an important role in cellular differentiation. DOK5 is upregulated in systemic Sclerosis and Associated with IGFBP-5-Induced fibrosis (PMID: 24551065). DOK5抗体

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