Anti-Islet 1抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-Islet 1抗体

Anti-Islet 1抗体

商家询价

产品名称: Anti-Islet 1抗体

英文名称: Islet 1

产品编号: YB--7532R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-Islet 1抗体

产品编号 YB-7532R
英文名称 Islet 1
中文名称 胰岛素基因增强结合蛋白1抗体
别    名 Insulin gene enhancer protein ISL 1; Insulin gene enhancer protein ISL-1; Insulin related protein; Isl 1; ISL LIM homeobox 1; ISL1; ISL1 transcription factor LIM homeodomain; ISL1 transcription factor, LIM/homeodomain (islet 1); ISL1 transcription factor, LIM/homeodomain; ISL1_HUMAN; Islet-1; Islet1.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 心血管  细胞生物  发育生物学  神经生物学  信号转导  干细胞  细胞类型标志物  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Horse, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Islet 1:201-300/349 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]

Function:
Binds to one of the cis-acting domain of the insulin gene enhancer.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.

Similarity:
Contains 1 homeobox DNA-binding domain. 
Contains 2 LIM zinc-binding domains.

SWISS:
P61371

Gene ID:
3670

Database links:

Entrez Gene: 396383 Chicken

Entrez Gene: 3670 Human

Entrez Gene: 16392 Mouse

Entrez Gene: 64444 Rat

Omim: 600366 Human

SwissProt: P50211 Chicken

SwissProt: P61371 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.