Cytochrome P450 2B1,细胞色素P450 2B1抗体

产品编号HZ-14177R
英文名称Cytochrome P450 2B1
中文名称细胞色素P450 2B1抗体
别 名 Cyp2b 1; Cyp2b 2; Cyp2b1; Cyp2b2; Cypbe; Cytochrome P450 2B1 + 2B2; Cype; CYPIIB1; CYPIIB2; Cytochrome P 450b; Cytochrome P 450b type e; Cytochrome P 450e M; Cytochrome P450 2B1; Cytochrome P450 2B2; Cytochrome P450 family 2 subfamily b polypeptide 1; Cytochrome P450 family 2 subfamily b polypeptide 2; Cytochrome P450 subfamily IIB phenobarbital inducible b e; ec 1.14.14.1; P450 PB4; P450-B; P450-LM2; P450-PB1 and P450-PB2; P450b; P450E; CP2B1_RAT.
说 明 书0.1ml 0.2ml
研究领域肿瘤 心血管 细胞生物 新陈代谢
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,
Cytochrome P450 2B1,细胞色素P450 2B1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量56kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from Rat Cytochrome P450 2B1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Cytochrome P450 2B1,细胞色素P450 2B1抗体PubMedPubMed
产品介绍background:
phenobarbitol-inducible member of the p450 xenobiotic-inducible superfamily involved in hydroxylation of decanoic and other fatty acids [RGD, Feb 2006]

Function:
The Cytochrome P450 superfamily of enzymes is one of three enzyme systems which metabolize the fatty acid arachadonic acid (AA) to regulators of vascular tone. P450 enzymes are monooxygenase enzymes which require several co-factors such as nicotinamide adenine dinucleotide phosphate (NADPH) and P450 reductase. There are over 200 known genes which encode P450s. Epoxygenases are those P450s which metabolize AA to epoxyeicosatrienoic acid (EETs) and omega-hydroxylases are those P450s which produce 19- and 20-hydroxyeicosatetraenoic acids (19- and 20-HETE). As well as fatty acid metabolism, P450s also metabolize many drugs and toxins. Cytochrome P450 3A4 is abundantly expressed in liver and small intestine and is inducible by barbiturates, glucocorticoids and rifampicin.

Subcellular Location:
Membrane bound, endoplasmic reticulum

Post-translational modifications:
Phosphorylation is accompanied by a decrease in enzyme activity.

Similarity:
Belongs to the cytochrome P450 family.

Gene ID:
24300

Database links:
Entrez Gene: 24300 Rat
Entrez Gene: 361523 Rat
SwissProt: P00176 Rat
SwissProt: P04167 Rat

Cytochrome P450 2B1,细胞色素P450 2B1抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.