KYNU抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
KYNU抗体

KYNU抗体

商家询价

产品名称： KYNU抗体

英文名称： KYNUAntibody

产品编号： XY11796-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
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 KYNU抗体

Applications
In-house applications ELISA, WB, IHC, IF     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
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  • 11796-1-AP;HeLa cellsHeLa cells were subjected to SDS PAGE followed by western blot with 11796-1-AP(KYNU antibody) at dilution of 1:2000
  • 11796-1-AP;human ovary tumorImmunohistochemical of paraffin-embedded human ovary tumor using 11796-1-AP(KYNU antibody) at dilution of 1:50 (under 10x lens)
  • 11796-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using KYNU antibody 11796-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Positive WB detected in HeLa cells
Positive IHC detected in Human ovary tumor tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:1000-1:10000
IHC : 1:20-1:200
IF : 1:10-1:100
 KYNU抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information KYNU抗体
Immunogen KYNU fusion protein ag2365 Full name Kynureninase (L-kynurenine hydrolase)
Calculated molecular
weight		 465aa,52 kDa;307aa,35 kDa Observed molecular 
weight		 52kd
GenBank accession 
number		 BC000879 Gene ID (NCBI) 8942
Gene symbol KYNU Synonyms KYNU, Kynureninase, L kynurenine hydrolase
Background

KYNU(kynureninase) is also named as L-kynurenine hydrolase and belongs to the kynureninase family. It is a pyridoxal-5'-phosphate-(pyridoxal-P)-depe11dent enzyme that catalyses the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively(PMID:8706755). In SDS-PAGE, it can detect a 48 kDa band lower than the preidicted molecular weight of 52 kDa due to limited proteolysis of the enzyme which might occur during handling of the protein(PMID:8706755). This protein is a 95-kD kD homodimer predominantly located in the cytoplasm(PMID:9180257). It has 2 isoforms produced by alternative splicing. KYNU抗体

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