ANGEL1,ANGEL1蛋白抗体

产品编号HZ-9741R
英文名称ANGEL1
中文名称ANGEL1蛋白抗体
别 名ANGE1_HUMAN; ANGEL1; KIAA0759; mKIAA0759; Protein angel homolog 1; angel homolog 1; RGD1306238.
规格价格0.1ml 0.2ml 
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
ANGEL1,ANGEL1蛋白抗体交叉反应Human, Mouse, Rat, Cow, Horse, Sheep,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量75kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ANGEL1
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
ANGEL1,ANGEL1蛋白抗体PubMedPubMed
产品介绍background:
ANGEL1 , also known as KIAA0759, is a 670 amino acid protein belonging to the CKR-4 protein family. ANGEL1 is encoded by a gene located on human chromosome 14, which contains about 700 genes and 106 million base pairs, making up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus on chromosome 14 and its fusion via translocation with the chromosome 19 encoded protein BCL3 may be related to B-cell malignancies.

Function:

Post-translational modifications:

DISEASE:

Similarity:
Belongs to the CCR4/nocturin family.

ANGEL1,ANGEL1蛋白抗体Database links:
Entrez Gene: 23357 Human
Entrez Gene: 68737 Mouse
SwissProt: Q9UNK9 Human
SwissProt: Q8VCU0 Mouse
Unigene: 497448 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.