Gly-Arg-Gly-Asp-Asn-Pro
产品名称: Gly-Arg-Gly-Asp-Asn-Pro
英文名称: Gly-Arg-Gly-Asp-Asn-Pro
产品编号: ONP10535
产品价格: 0
产品产地: 中国,杭州
品牌商标: Ontores
更新时间: null
使用范围: null
浙江鸿拓生物技术有限公司
- 联系人 :
- 地址 : 上海浦东新区蔡伦路781号A1201室(上海办事处)
- 邮编 : 201203
- 所在区域 : 上海
- 电话 : 185****7060 点击查看
- 传真 : 点击查看
- 邮箱 : zhg@ontores.cn
G-R-G-D-N-P is a superior inhibitor of cell attachment to fibronectin and a weak inhibitor of cell attacment to vitronectin. It also inhibits binding of fibrinogen, fibronectin, vitronectin and von Willebrand factor to platelets and resists to carboxypeptidases. G-R-G-D-N-P induces apoptosis in various cell types and cell lines at 1mM by a mechanism involving cellular uptake and possible direct stimulation of procaspase-3 autoprocessing. It contains the motif RGD (Arg-Gly-Asp) which is found in many integrin ligands. G-R-G-D-N-P inhibits cell adhesion to fibronectin 80-90% at 1 mM.