重组小鼠IL-5-RNAi技术-试剂-生物在线
上海沪震实业有限公司
重组小鼠IL-5

重组小鼠IL-5

商家询价

产品名称： 重组小鼠IL-5

英文名称： Recombinant Murine Interleukin-5

产品编号： HZ4683

产品价格： 0

产品产地： 中国/上海

品牌商标： 沪震生物

更新时间： 2023-08-17T10:24:20

使用范围： null

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 重组小鼠IL-5

中文名称：重组小鼠IL-5
英文名称：Recombinant Murine Interleukin-5
产品规格：5μg
分子量：Approximately 26.2kDa,a disulfide-linked homodimeric protein containing two 113 amino acids.
储存条件：冷冻（-20℃）

概述

IL-5,also named B-cell differentiation factor I,eosinophil differentiation factor and TRF,is belonging to the cytokine family and the IL-5 gene is in close proximity to the genes encoding IL-3,IL-4,and granulocyte-macrophage colony-stimulating factor(GM-CSF),which are often co-expressed in TH2 cells.Through binding to the IL-5 receptor,IL-5 stimulates B cell growth and increases immunroglobulin secretion.It is also a key mediator in eosinophil activation.Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma.Murine IL-5 is a 113-amino acid(115 in human,113 in rat)-long TH2 cytokine that is part of the hematopoietic family.Unlike other members of this cytokine family(namely IL-3 and GM-CSF),this glycoprotein in its active form is a homodimer.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格
 

外观 Sterile Filtered White lyophilized(freeze-dried)powder.
纯度 ＞98%by SDS-PAGE and HPLC analyses.
来源 Escherichia coli.
生物活性 Fully biologically active when compared to standard.The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2ng/ml,corresponding to a specific activity of>5.0×105 IU/mg.
成分 Lyophilized from a 0.2μmfiltered concentrated solution in 20mMTris,pH 9.0,150 mM NaCl.
内毒素 Less than 0.1 EU/μg of rMuIL-5 as determined by LAL method.
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/ml.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列 MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG

 

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