SNAP23,突触相关蛋白23抗体

产品编号HZ-11362R
英文名称SNAP23
中文名称突触相关蛋白23抗体
别 名SNAP 23; SNAP-23; SNAP23; SNAP23A; SNAP23B; SNP23_HUMAN; Synaptosomal associated protein 23; Synaptosomal associated protein 23kDa; Synaptosomal associated protein; Synaptosomal-associated protein 23; Vesicle membrane fusion protein SNAP 23; Vesicle membrane fusion protein SNAP23; Vesicle-membrane fusion protein SNAP-23; HsT17016.
说 明 书0.1ml 0.2ml
研究领域神经生物学 细胞类型标志物 细胞膜蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
SNAP23,突触相关蛋白23抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量23kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human SNAP23
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
SNAP23,突触相关蛋白23抗体PubMedPubMed
产品介绍background:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Function:
Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion.

Subunit:
Homotetramer (via coiled-coil domain), also forms heterotetramers with STX4 and VAMP3. Binds simultaneously to SNAPIN and SYN4. Found in a complex with VAMP8 and STX4 in pancreas. Interacts with STX1A and STX12 (By similarity). Binds tightly to multiple syntaxins and synaptobrevins/VAMPs. Found in a complex with VAMP8 and STX1A.

Subcellular Location:
Cell membrane. Cell membrane. Cell junction > synapse > synaptosome. Mainly localized to the plasma membrane.

Tissue Specificity:
Ubiquitous. Highest levels where found in placenta.

Similarity:
Belongs to the SNAP-25 family.
Contains 2 t-SNARE coiled-coil homology domains.

Database links:
Entrez Gene: 453365 Chimpanzee
Entrez Gene: 522423 Cow
Entrez Gene: 478268 Dog
Entrez Gene: 101141000 Gorilla
Entrez Gene: 8773 Human
Entrez Gene: 20619 Mouse
Entrez Gene: 100174679 Orangutan
Entrez Gene: 64630 Rat
Omim: 602534 Human
SwissProt: O00161 Human
SwissProt: O09044 Mouse
SwissProt: O70377 Rat
Unigene: 511149 Human
Unigene: 245715 Mouse
Unigene: 14789 Rat

SNAP23,突触相关蛋白23抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.