MODY1/CEN20q FISH Probe
产品名称: MODY1/CEN20q FISH Probe
英文名称: MODY1/CEN20q FISH Probe
产品编号: FG0082
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene amplification using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - MODY1
Approximately 480kb
Texas Red
20q13.12
- Probe 2:
Size:
Fluorophore:
Location: - CEN20q
Approximately 680kb
FITC
20q11.22
- Probe Gap:
- The gap between two probes is approximately 6,120 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge this image
- Human colon adenocarcinoma (FFPE) stained with MODY1/CEN20q FISH Probe. Human colon adenocarcinoma showed no MODY1 gene amplification.
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
- enlarge
- Entrez GeneID:
- 3172
- Gene Name:
- HNF4A
- Gene Alias:
- FLJ39654,HNF4,HNF4a7,HNF4a8,HNF4a9,MODY,MODY1,NR2A1,NR2A21,TCF,TCF14
- Gene Description:
- hepatocyte nuclear factor 4, alpha
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- HNF4-alpha,OTTHUMP00000031060,OTTHUMP00000031062,hepatic nuclear factor 4 alpha,hepatocyte nuclear factor 4 alpha,transcription factor-14
- Interactome
- Gene Pathway
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Birth Weight
- Breast cancer
- Breast Neoplasms
- Calcinosis
- Cardiovascular Diseases
- Colitis, Ulcerative
- Coronary Artery Disease
- Diabetes Complications
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetes, Gestational
- Diabetic Nephropathies
- Disease Progression
- Disease Susceptibility
- Dyslipidemias