产品概述：Recombinant protein of human transcription factor binding to IGHM enhancer 3 (TFE3), with N-terminal polyhistidine tag, expressed in sf9 cells.

蛋白长度：A DNA sequence from GoldORF clone, [GH36740V], encoding human full-length TFE3

表达系统：Sf9

种属：Human

标签类型：N-His

分子量：62 kDa

通用名：TFE3

总结：This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：50mM Tris-HCl pH8.0, 150mM NaCl, 10%glycerol

别名：bHLHe33; RCCP2; RCCX1; TFEA