ADAM8抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
ADAM8抗体

ADAM8抗体

商家询价

产品名称： ADAM8抗体

英文名称： ADAM8Antibody

产品编号： XY23778-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 ADAM8抗体

Applications
Tested Applications: ELISA, WB, IHC
Specificity Reaction: Human, Mouse; Other species are not tested.Please decide the specificity by homology
Positive WB detected in BxPC-3 cells, mouse pancreas tissue
Positive IHC detected in Human tonsillitis tissue, human pancreas tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
 ADAM8抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 23778-1-AP;BxPC-3 cellsBxPC-3 cells were subjected to SDS PAGE followed by western blot with 23778-1-AP( ADAM8 Antibody) at dilution of 1:600
  • 23778-1-AP;human tonsillitis tissueImmunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 23778-1-AP( ADAM8 Antibody) at dilution of 1:50 (under 10x lens)
  • 23778-1-AP;human tonsillitis tissueImmunohistochemistry of paraffin-embedded human tonsillitis tissue slide using 23778-1-AP( ADAM8 Antibody) at dilution of 1:50 (under 40x lens)
Product Information ADAM8抗体
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen Information
Immunogen: ADAM8 fusion protein ag17262 Full Name: ADAM metallopeptidase domain 8
Caculated Molecular
Weight:		 824aa,89 kDa Observed Molecular 
Weight:		 65 kDa
GenbankNo BC115404 GeneID: 101
Symbol ADAM8 Synonyms ADAM metallopeptidase domain 8, ADAM8, ADAM8 protein, CD156, MS2
Background

ADAMs are a large family of transmembrane proteins that are involved in proteolysis, making them candidates for mediating the remodeling of the extracellular matrix(ECM). ADAM8, one of the members of the ADAM family, is overexpressed in various human tumors. It has been shown previously that hypoxia influences the expression of some ADAM proteins. The protein found to be expressed in two active forms(90 kDa and 60 kDa): potential shedding protein and remnant protein in the pancreatic tissues under chronic pancreatitis and pancreatic cancer(PMID:18566576). The full length protein has a signal peptide and four glycosylation sites. This antibody is specific to ADAM8. ADAM8抗体

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