Anti-NNP1抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-NNP1抗体

Anti-NNP1抗体

商家询价

产品名称: Anti-NNP1抗体

英文名称: NNP1

产品编号: YB--9300R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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Anti-NNP1抗体

产品编号 YB-9300R
英文名称 NNP1
中文名称 新型核蛋白质1抗体
别    名 NNP 1; NNP-1; NNP1; Nnp1 homolog nucleolar protein; Novel nuclear protein 1; Nucleolar protein Nop52; Protein NNP 1; Protein NNP1; Ribosomal RNA processing 1 homolog; Ribosomal RNA processing protein 1 homolog A; rrp1; RRP1 like protein; RRP1-like protein; RRP1_HUMAN; RRP1A.  
规格价格 100ul/1580元 购买    200ul/2480元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 细胞生物  细胞周期蛋白  细胞分化  表观遗传学  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Rabbit, 
产品应用 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:50-200 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
细胞定位 细胞核 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NNP1/RRP1 like protein:261-360/461 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
Novel nuclear protein 1 (NNP-1), also known as RRP1-like protein or Nucleolar protein Nop52, is a 461 amino acid protein belonging to the RRP1 family. Localized to the nucleolus, NNP-1 has simian virus 40-type and bipartite nuclear localization signals and four coiled-coil domains within its C-terminal region. NNP-1 has been found to play an important role in the generation of 28S rRNA in the late processing steps of ribosome biogenesis. At the end of mitosis, nucleolar proteins assemble in a sequential order during the rebuilding of the nucleolus. NNP-1 assembles after Fibrillarin and C23, and simultaneously with B23 and POP1 in the prenucleolar body pathway. 

Function:
Plays a critical role in the generation of 28S rRNA.

Subunit:
Interacts with C1QBP.

Subcellular Location:
Nucleus, nucleolus.

Tissue Specificity:
Ubiquitously expressed in fetal and adult tissues.

Similarity:
Belongs to the RRP1 family.

SWISS:
Q14684

Gene ID:
23076

Database links:

Entrez Gene: 23076 Human

Entrez Gene: 72462 Mouse

Entrez Gene: 309673 Rat

Omim: 610654 Human

SwissProt: Q14684 Human

SwissProt: Q91YK2 Mouse

Unigene: 654727 Human

Unigene: 54275 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications