Annexin VI,膜粘连蛋白6抗体

产品编号HZ-8997R
英文名称Annexin VI
中文名称膜粘连蛋白6抗体
别 名Annexin VI; 67 kDa calelectrin; Annexin A6; Annexin VI p68; AnnexinA6; AnnexinVI; ANX 6; ANX A6; ANX6; ANXA 6; ANXA6; Calcium binding protein p68; Calelectrin; Calphobindin II; CalphobindinII; CBP 68; CBP68; Chromobindin 20; Chromobindin20; CPB II; CPBII; Lipocortin VI; LipocortinVI; p68; P70; Protein III; ProteinIII.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 结合蛋白 细胞膜蛋白
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Chicken, Dog, Pig,
Annexin VI,膜粘连蛋白6抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量67-74kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Annexin VI
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Annexin VI,膜粘连蛋白6抗体PubMedPubMed
产品介绍background:
The Annexin family of calcium binding proteins is composed of at least ten mammalian genes. It is characterised by a conserved core domain which binds to phospholipids in a Ca2+ dependent manner and a unique amino terminal region which may confer binding specificity. The Annexin family has been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. When overexpressed in A431 cells, Annexin VI causes a partial reversal of the transformed phenotype.

Function:
May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.

Tissue Specificity:
Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Post-translational modifications:
Phosphorylated in response to growth factor stimulation.

Similarity:
Belongs to the annexin family.
Contains 8 annexin repeats.

Gene ID:
309

Annexin VI,膜粘连蛋白6抗体Database links:
Entrez Gene: 309 Human
Entrez Gene: 11749 Mouse
Entrez Gene: 79125 Rat
Omim: 114070 Human
SwissProt: P08133 Human
SwissProt: P14824 Mouse
SwissProt: P48037 Rat
Unigene: 412117 Human
Unigene: 265347 Mouse
Unigene: 204053 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.