Product Description: Stat5 antibody was developed using short peptide based on human Stat5.  The antibodies were test against human and mouse cell lysate and mouse tissue (spleen) extract to detect the Stat5.

Species: Rabbit

Formulation: 250 µg/mL in PBS, pH7 with 50% Glycerol.

Storage & Stability: Store product at –20 ^_℃.  Three years from date of shipping.

Immunogen: Human Stat5 (690-712 aa) peptide KLH conjugates.

Purification: Peptide-affinity chromatography.

Specificity: The antibody recognizes recognizes Stat5 in human and mouse. .

Applications: ELISA(1: 2500), WB(1:2500), Immunohistochemistry(1:100).

Scientific Description: STAT1 and STAT2 were the first two STATs (signal transducers and activators of transcription) proteins discovered. They are involved in interferon-alpha (IFN-alpha) and IFN-gamma signal transduction. Other STAT proteins that have been identified are STAT3, 4, 5a, 5b, and 6. ^[1] Specific functions of the STAT proteins are poorly understood. They are thought to be involved in a variety of systems including antiviral responses and cell transformation. ^[2]

References: 1. Cell, 84: 331-334, 1996.

2. Eur. J. Biochem., 248: 615-633, 1997.