FITC标记的ELOVL7蛋白抗体
产品名称: FITC标记的ELOVL7蛋白抗体
英文名称: Anti-ELOVL7/FITC
产品编号: HZ-14573R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: ICC=1:50-200 IF=1:50-200
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Rabbit Anti-ELOVL7/FITC Conjugated antibody
FITC标记的ELOVL7蛋白抗体 |
英文名称 | Anti-ELOVL7/FITC |
中文名称 | FITC标记的ELOVL7蛋白抗体 |
别 名 | 3-keto acyl-CoA synthase Elovl7; Elongation of very long chain fatty acids protein 7; ELOV7_HUMAN; ELOVL family member 7 elongation of long chain fatty acids; ELOVL family member 7 elongation of long chain fatty acids yeast; ELOVL fatty acid elongase 7; ELOVL7. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 信号转导 新陈代谢 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, |
产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 33kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ELOVL7 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈. |
产品介绍 | background: Elongation of very long chain fatty acid-like (ELOVL) proteins are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. Fatty acids are important in many biological processes including fetal growth and development, brain development, inflammatory response, and retinal function. The ELOVL proteins function as elongases and catalyze fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 7 (ELOVL7) is involved in lipogenesis and its expression is regulated by PPAR? ELOVL7 is a 281 amino acid protein and the gene encoding ELOVL7 maps to chromosome 5q12.1. Function: Condensing enzyme that catalyzes the synthesis of saturated and polyunsaturated very long chain fatty acids. Highest activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs. Subcellular Location: Endoplasmic reticulum membrane. Tissue Specificity: Expressed in most tissues except heart and skeletal muscle. Similarity: Belongs to the ELO family. Database links: Entrez Gene: 79993 Human Entrez Gene: 74559 Mouse SwissProt: A1L3X0 Human SwissProt: Q9D2Y9 Mouse Unigene: 274256 Human Unigene: 286127 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
超长链脂肪酸样蛋白(ELOVL)的伸长是ELO蛋白家族的成员,在组织特异性生物合成超长链脂肪酸和鞘脂中起着重要作用。脂肪酸在许多生物过程中都很重要,包括胎儿生长发育、大脑发育、炎症反应和视网膜功能。ELOVL蛋白具有伸长酶的功能,催化脂肪酸的伸长还原并定位于内质网(ER)。长链脂肪酸蛋白7(ELVL7)的延伸参与脂肪生成,其表达受PPAR调控。ELOVL7是一个281氨基酸的蛋白质,编码EOVL7的基因被映射到染色体5q121。