Anti-phospho-RGS19 (Ser151)抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-phospho-RGS19 (Ser151)抗体

Anti-phospho-RGS19 (Ser151)抗体

商家询价

产品名称: Anti-phospho-RGS19 (Ser151)抗体

英文名称: phospho-RGS19 (Ser151)

产品编号: YB--5688R

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-phospho-RGS19 (Ser151)抗体

产品编号 YB-5688R
英文名称 phospho-RGS19 (Ser151)
中文名称 磷酸化G蛋白信号转导调节因子19抗体
别    名 RGS19(phospho S151); RGS19(phospho Ser151); G alpha interacting protein; GAIP; GNAI3IP; Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G protein signalling 19; RGSGAIP; RGS19_HUMAN; Regulator of G-protein signaling 19; RGS19; G-alpha-interacting protein.  
规格价格 100ul/1580元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 肿瘤  免疫学  信号转导  细胞凋亡  转录调节因子  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, 
产品应用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
细胞定位 细胞膜 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human RGS19 around the phosphorylation site of Ser151:IL(p-S)PK 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background:
G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase activating protein that functions to down regulate Galpha i/Galpha q linked signaling.

Function:
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.

Subunit:
Interacts with GIPC PDZ domain.

Subcellular Location:
Membrane; Lipid-anchor.

Tissue Specificity:
Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.

Post-translational modifications:
Fatty acylated. Heavily palmitoylated in the cysteine string motif.
Phosphorylated, mainly on serine residues.

Similarity:
Contains 1 RGS domain.

SWISS:
P49795

Gene ID:
10287

Database links:

Entrez Gene: 10287 Human

Entrez Gene: 56470 Mouse

Entrez Gene: 59293 Rat

Omim: 605071 Human

SwissProt: P49795 Human

SwissProt: Q9CX84 Mouse

SwissProt: O70521 Rat

Unigene: 422336 Human

Unigene: 274366 Mouse

Unigene: 88166 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.