Anti-phospho-RGS19 (Ser151)抗体
产品名称: Anti-phospho-RGS19 (Ser151)抗体
英文名称: phospho-RGS19 (Ser151)
产品编号: YB--5688R
产品价格: null
产品产地: 中国/美国
品牌商标: Ybscience
更新时间: 2023-08-17T10:29:50
使用范围: 科研使用
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Anti-phospho-RGS19 (Ser151)抗体
产品编号 | YB-5688R |
英文名称 | phospho-RGS19 (Ser151) |
中文名称 | 磷酸化G蛋白信号转导调节因子19抗体 |
别 名 | RGS19(phospho S151); RGS19(phospho Ser151); G alpha interacting protein; GAIP; GNAI3IP; Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; Regulator of G protein signalling 19; RGSGAIP; RGS19_HUMAN; Regulator of G-protein signaling 19; RGS19; G-alpha-interacting protein. |
规格价格 | 100ul/1580元 购买 大包装/询价 |
说 明 书 | 100ul |
产品类型 | 磷酸化抗体 |
研究领域 | 肿瘤 免疫学 信号转导 细胞凋亡 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, |
产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 25kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from human RGS19 around the phosphorylation site of Ser151:IL(p-S)PK |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
PubMed | PubMed |
产品介绍 | background: G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase activating protein that functions to down regulate Galpha i/Galpha q linked signaling. Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein. Subunit: Interacts with GIPC PDZ domain. Subcellular Location: Membrane; Lipid-anchor. Tissue Specificity: Highest expression in lung. Placenta, liver and heart also express high levels of GAIP. Post-translational modifications: Fatty acylated. Heavily palmitoylated in the cysteine string motif. Phosphorylated, mainly on serine residues. Similarity: Contains 1 RGS domain. SWISS: P49795 Gene ID: 10287 Database links: Entrez Gene: 10287 Human Entrez Gene: 56470 Mouse Entrez Gene: 59293 Rat Omim: 605071 Human SwissProt: P49795 Human SwissProt: Q9CX84 Mouse SwissProt: O70521 Rat Unigene: 422336 Human Unigene: 274366 Mouse Unigene: 88166 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |