ABI3,ABI基因家族2抗体

产品编号HZ-5985R
英文名称ABI3
中文名称ABI基因家族2抗体
别 名ABI gene family member 3; Nesh; New molecule including SH3; ABI3_HUMAN.
规格价格0.1ml 0.2ml 
说 明 书0.1ml 0.2ml
研究领域肿瘤 免疫学 染色质和核信号
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
ABI3,ABI基因家族2抗体产品应用ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量39kDa
细胞定位细胞浆
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ABI3
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ABI3,ABI基因家族2抗体PubMedPubMed
产品介绍background:
ABI3 is thought to inhibit tumor metastasis. In vitro, ABI3 reduces cell motility.

Function:
May inhibit tumor metastasis. In vitro, reduces cell motility.

Subunit:
May interact with PAK1 and PAK2. Probably interacts with TARSH.

Subcellular Location:
Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells.

Tissue Specificity:
Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle.

Similarity:
Belongs to the ABI family.
Contains 1 SH3 domain.

Gene ID:
25890

Database links:
Entrez Gene: 538604 Cow
Entrez Gene: 478544 Dog
Entrez Gene: 100723639 Guinea pig
Entrez Gene: 25890 Human
Entrez Gene: 320712 Mouse
Entrez Gene: 100154641 Pig
Entrez Gene: 363767 Rat
Entrez Gene: 100149890 Zebrafish
Omim: 606279 Human
ABI3,ABI基因家族2抗体SwissProt: Q7Z7G0 Human
Unigene: 477015 Human
Unigene: 209236 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.