产品概述：Purified recombinant protein of Human DNA-damage-inducible transcript 3 (DDIT3), transcript variant 5, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

蛋白长度：A DNA sequence encoding human full-length DDIT3

表达系统：E. coli

种属：Human

标签类型：N-GST and C-His

分子量：45 kDa

通用名：DDIT3

总结：This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

别名：AltDDIT3; C/EBPzeta; CEBPZ; CHOP; CHOP-10; CHOP10; GADD153