Anti-Phospho-GCN2 (Thr899)/FITC Conjugated抗体-抗体-抗体-生物在线
上海钰博生物科技有限公司
Anti-Phospho-GCN2 (Thr899)/FITC Conjugated抗体

Anti-Phospho-GCN2 (Thr899)/FITC Conjugated抗体

商家询价

产品名称: Anti-Phospho-GCN2 (Thr899)/FITC Conjugated抗体

英文名称: Anti-Phospho-GCN2 (Thr899)/FITC

产品编号: YB--3155R-FITC

产品价格: null

产品产地: 中国/美国

品牌商标: Ybscience

更新时间: 2023-08-17T10:29:50

使用范围: 科研使用

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 Anti-Phospho-GCN2 (Thr899)/FITC Conjugated抗体

产品编号 YB-3155R-FITC
英文名称 Anti-Phospho-GCN2 (Thr899)/FITC
中文名称 FITC标记的磷酸化蛋白激酶GCN2蛋白抗体
别    名 GCN2 (phospho T899); p-GCN2 (phospho T899); EIF2AK4; Eukaryotic Translation Initiation Factor 2-alpha kinase 4; GCN2-like protein; KIAA1338; E2AK4_HUMAN; Eif2ak4; Eukaryotic Translation Initiation Factor 2 alpha kinase 4; GCN2; GCN2 eIF2alpha kinase; GCN2-like protein; MGCN2.  
规格价格 100ul/2980元 购买        大包装/询价
说 明 书 100ul  
产品类型 磷酸化抗体 
研究领域 肿瘤  细胞生物  染色质和核信号  神经生物学  信号转导  激酶和磷酸酶  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Cow, Horse, 
产品应用 Flow-Cyt=3ug/Test  
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 189kDa
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human GCN2 around the phosphorylation site of Thr899
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍 background:
GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses.

Function:
Can phosphorylate the alpha subunit of EIF2 and may mediate translational control.

Tissue Specificity:
Widely expressed.

Post-translational modifications:
Autophosphorylated on threonine residues.

Similarity:
Belongs to the protein kinase superfamily.
Ser/Thr protein kinase family. GCN2 subfamily.
Contains 2 protein kinase domains.
Contains 1 RWD domain.

Database links:

Entrez Gene: 440275 Human

Entrez Gene: 27103 Mouse

Entrez Gene: 114859 Rat

Omim: 609280 Human

SwissProt: Q9P2K8 Human

SwissProt: Q9QZ05 Mouse

Unigene: 656673 Human

Unigene: 217616 Mouse

Unigene: 8333 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

GCN2蛋白的作用;可能是将短期记忆变成长期记忆的一个主控调节因子, GCN2蛋白在长期记忆形成中功能的发现将可能帮助研究人员开发出提高记忆力丧失的病人提高记忆力