Salusin alpha,心血管调节肽Salusin-α抗体

产品编号HZ-9875R
英文名称Salusin alpha
中文名称心血管调节肽Salusin-α抗体
别 名Prosalusin precursor; TOR2A; TORP1; Torsin 2A [Precursor]; Torsin family 2 member A; Torsin related protein 1; TOR2A_HUMAN.
说 明 书0.1ml 0.2ml
研究领域心血管 免疫学 神经生物学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Cow,
Salusin alpha,心血管调节肽Salusin-α抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量33kDa
细胞定位分泌型蛋白
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human Salusin alpha
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Salusin alpha,心血管调节肽Salusin-α抗体PubMedPubMed
产品介绍background:
Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.

Subcellular Location:
Secreted.

Tissue Specificity:
Isoform 1 is expressed ubiquitously, except in cardiac and endothelial tissues.

Similarity:
Belongs to the clpA/clpB family. Torsin subfamily.

Gene ID:
27433

Database links:
Entrez Gene: 27433 Human
Omim: 608052 Human
SwissProt: Q5JU69 Human
Unigene: 444106 Human

Salusin alpha,心血管调节肽Salusin-α抗体Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.