ROS1 Split FISH Probe
产品名称： ROS1 Split FISH Probe
英文名称： ROS1 Split FISH Probe
产品编号： FS0015
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Labeled FISH probes for identification of gene split using Fluoresecent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Quality Control Testing:
- Representative images of normal human cell (lymphocyte) stain with the dual color FISH probe. The left image is chromosomes at metaphase, and the right image is an interphase nucleus.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Note:
- Hybridization position of the probes on the chromosome:
-
- Probe 1:
Size:
Fluorophore:
Location: - ROS1(Texas Red)
Approximately 250kb
Texas Red
6q22.1
- Probe 2:
Size:
Fluorophore:
Location: - ROS1(FITC)
Approximately 720kb
FITC
6q22.1
- Probe Gap:
- The length of overlap between two probes is approximately 60 kb.
- Origin:
- Human
- Source:
- Genomic DNA
- Regulation Status:
- For research use only (RUO)
- Publication Reference
- 1.
- ROS1 Receptor Tyrosine Kinase, a Druggable Target, is Frequently Overexpressed in Non-Small Cell Lung Carcinomas Via Genetic and Epigenetic Mechanisms.
Lee HJ, Seol HS, Kim JY, Chun SM, Suh YA, Park YS, Kim SW, Choi CM, Park SI, Kim DK, Kim YH, Jang SJ.Ann Surg Oncol. 2012 Aug 23.
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Huma lung, adenosquamous cell carcinoma (FFPE) stained with ROS1 Split FISH Probe. Human lung, adenosquamous cell carcinoma showed no ROS gene split.
- Protocol Download
- Fluorescent In Situ Hybridization (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Human lung cancer (FFPE) stained with ROS1 Split FISH Probe. Human lung cancer showed ROS1 gene split.
- Protocol Download
- Entrez GeneID:
- 6098
- Gene Name:
- ROS1
- Gene Alias:
- MCF3,ROS,c-ros-1
- Gene Description:
- c-ros oncogene 1 , receptor tyrosine kinase
- Omim ID:
- 165020
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq
- Other Designations:
- OTTHUMP00000017814,OTTHUMP00000040389,proto-oncogene c-ros-1 protein,proto-oncogene tyrosine-protein kinase ROS,transmembrane tyrosine-specific protein kinase,v-ros UR2 sarcoma virus oncogene homolog 1,v-ros avian UR2 sarcoma virus oncogene homolog 1
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- Atherosclerosis
- Brain Ischemia
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- Cerebral Hemorrhage
- Coronary Artery Disease
- Coronary Disease
- Coronary Restenosis
- Genetic Predisposition to Disease
- Hypertension
- Kidney Failure, Chronic
- Lung Neoplasms
- Metabolic Syndrome X
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- Pulmonary Disease, Chronic Obstructive
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