CASPASE 8/P18 抗体
Applications
| In-house applications |
ELISA, WB, IHC, IP, IF Application not tested? Please see our Guarantee. |
| Published applications |
IF, WB |
Publications |
27 citations –view here |
| Species specificity |
Human, Mouse; other species not tested. |
| Published Species |
Human, mouse, rat |
|
Images
Prev12Next
 HepG2 cells were subjected to SDS PAGE followed by western blot with 13423-1-AP(CASP8 antibody) at dilution of 1:1000 IP Result of anti-CASP8 (IP:13423-1-AP, 3ug; Detection:13423-1-AP 1:500) with HeLa cells lysate 2500ug. Immunohistochemical of paraffin-embedded human lymphoma using 13423-1-AP(CASP8 antibody) at dilution of 1:50 (under 10x lens) Immunohistochemical of paraffin-embedded human lymphoma using 13423-1-AP(CASP8 antibody) at dilution of 1:50 (under 40x lens) Immunofluorescent analysis of HepG2 cells using 13423-1-AP( Caspase 8 Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG
|
| Positive WB detected in |
HepG2 cells, HeLa cells, Raji cells, RAW264.7 cells, UV treated Hela cells |
| Positive IP detected in |
HeLa cells |
| Positive IHC detected in |
Human lymphoma tissue, human colon tissue |
| Positive IF detected in |
HepG2 cells |
| Recommended dilution |
WB : 1:200-1:2000
IP : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100 |
CASPASE 8/P18 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
| Source |
Rabbit |
Purification method |
Antigen affinity purification |
| Isotype |
IgG |
Storage |
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. |
Immunogen Information
| Immunogen |
Caspase 8/p18 fusion protein ag4214 |
Full name |
Caspase 8, apoptosis-related cysteine peptidase |
Calculated molecular
weight |
538aa,62 kDa |
Observed molecular
weight |
50-55 kDa,25-32 kDa |
GenBank accession
number |
BC028223 |
Gene ID (NCBI) |
841 |
| Gene symbol |
CASP8 |
Synonyms |
Apoptotic protease Mch 5, Casp 8, CASP8, Caspase 8, Caspase 8/p18, FADD like ICE, FLICE, ICE like apoptotic protease 5, MCH5 |
Background CASPASE 8/P18 抗体
|
CASP8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. CASP8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816 ). It may control diabetic embryopathy-associated apoptosis via regulation of the Bid-stimulated mitochondrion/caspase-9 pathway(PMID:19194987). CASP8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. CASPASE 8/P18 抗体
|
XY220Ra21 博来霉素水解酶(BLMH)单克隆抗体 Monoclonal Antibody to Bleomycin Hydrolase (BLMH) Rattus norvegicus (Rat)
XY299Hu21 载脂蛋白M(APOM)单克隆抗体 Monoclonal Antibody to Apolipoprotein M (APOM) Homo sapiens (Hukl)
XY775Ra21 络丝蛋白(RL)单克隆抗体 Monoclonal Antibody to Reelin (RL) Rattus norvegicus (Rat)
XY915Hu21 成纤维细胞生长因子13(FGF13)单克隆抗体 Monoclonal Antibody to Fibroblast Growth Factor 13 (FGF13) Homo sapiens (Hukl)
XY060Ra21 70kDa热休克蛋白2(HSPA2)单克隆抗体 Monoclonal Antibody to Heat Shock 70kDa Protein 2 (HSPA2) Rattus norvegicus (Rat)
XY353Ra21 Slit同源物3(Slit3)单克隆抗体 Monoclonal Antibody to Slit Homolog 3 (Slit3) Rattus norvegicus (Rat)
XY744Hu21 脂解激活脂蛋白受体(LSR)单克隆抗体 Monoclonal Antibody to Lipolysis Stimulated Lipoprotein Receptor (LSR) Homo sapiens (Hukl)
XY796Hu21 精氨酸酶Ⅱ(Arg2)单克隆抗体 Monoclonal Antibody to Arginase II (Arg2) Homo sapiens (Hukl)
XY922Hu21 唾液酸结合Ig样凝集素9(SIGLEC9)单克隆抗体 Monoclonal Antibody to Sialic Acid Binding Ig Like Lectin 9 (SIGLEC9) Homo sapiens (Hukl)
XY570Ra21 α1-B-糖蛋白(α1BG)单克隆抗体 Monoclonal Antibody to Alpha-1-B-Glycoprotein (a1BG) Rattus norvegicus (Rat)
XY354Hu21 晶状体蛋白λ1(CRYλ1)单克隆抗体 Monoclonal Antibody to Crystallin Lambda 1 (CRYl1) Homo sapiens (Hukl)
XY097Hu21 亚硫酸盐氧化酶(SUOX)单克隆抗体 Monoclonal Antibody to Sulfite Oxidase (SUOX) Homo sapiens (Hukl)
XY776Hu21 中间α-球蛋白抑制因子H4(ITIH4)单克隆抗体 Monoclonal Antibody to Inter Alpha-Globulin Inhibitor H4 (ITIH4) Homo sapiens (Hukl)
XY048Ra21 胃动蛋白2(GKN2)单克隆抗体 Monoclonal Antibody to Gastrokine 2 (GKN2) Rattus norvegicus (Rat)
XY928Hu21 干扰素γ诱导单核因子(MIγ)单克隆抗体 Monoclonal Antibody to Monokine Induced By Interferon Gamma (MIg) Homo sapiens (Hukl)
