Anti-SLC27A5抗体
产品名称： Anti-SLC27A5抗体
英文名称： SLC27A5
产品编号： YB--4088R
产品价格： null
产品产地： 中国/美国
品牌商标： Ybscience
更新时间： 2023-08-17T10:29:50
使用范围： 科研使用
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Anti-SLC27A5抗体
| 产品编号 | YB-4088R |
| 英文名称 | SLC27A5 |
| 中文名称 | 脂肪酸转运蛋白5抗体 |
| 别 名 | ACSB; ACSVL6; BA CoA ligase; BACS; BAL; Bile acid CoA ligase; Bile acyl CoA synthetase; Cholate CoA ligase; FACVL3; FATP 5; FATP5; Fatty acid Coenzyme A ligase very long chain 3; Fatty acid transport protein 5; Solute carrier family 27 (fatty acid transporter) member 5; Solute carrier family 27 member 5; Very long chain acyl CoA synthetase homolog 2; Very long chain acyl CoA synthetase related protein; VLACS related; VLACSR; VLCS H2; VLCSH2; S27A5_HUMAN. |
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Specific References (1) | bs-4088R has been referenced in 1 publications.
[IF=2.25] Han, Ying, et al. "Basis of aggravated hepatic lipid metabolism by chronic stress in high-fat diet-fed rat." Endocrine: 1-10. WB ; Rat.
PubMed:24895043
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| 规格价格 | 100ul/1580元 购买 200ul/2480元 购买 大包装/询价 |
| 说 明 书 | 100ul 200ul |
| 研究领域 | 肿瘤 免疫学 染色质和核信号 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Cow, Horse, Sheep, |
| 产品应用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 75kDa |
| 细胞定位 | 细胞浆 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC27A5:251-350/690 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: SLC27A5 is an isozyme of very long chain acyl CoA synthetase (VLCS). It is an acyl CoA synthetase involved in bile acid metabolism and is proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. It seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, it also activates 3 alpha,7 alpha,12 alpha trihydroxy 5 beta cholestanate (THCA), the C27 precursor of cholic acid derived from the de novo synthesis from cholesterol. Function: Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein. Tissue Specificity: Predominantly expressed in liver. Similarity: Belongs to the ATP-dependent AMP-binding enzyme family. SWISS: Q9Y2P5 Gene ID: 10998 Database links: Entrez Gene: 10998 Human Entrez Gene: 26459 Mouse Omim: 603314 Human SwissProt: Q9Y2P5 Human SwissProt: Q4LDG0 Mouse Unigene: 292177 Human Unigene: 10984 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |