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上海信裕生物科技有限公司
ASGR2抗体

ASGR2抗体

商家询价

产品名称： ASGR2抗体

英文名称： ASGR2Antibody

产品编号： XY11501-2

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 ASGR2抗体

Applications
In-house applications ELISA, WB, IP, FC     Application not tested? Please see our Guarantee.
Species specificity Human; other species not tested.
Images
Prev1NextView more validation data
  • 11501-2-AP;human liver tissuehuman liver tissue were subjected to SDS PAGE followed by western blot with 11501-2-AP(ASGR2 antibody) at dilution of 1:400
  • 11501-2-AP;L02 cellsIP Result of anti-ASGR2 (IP:11501-2-AP, 4ug; Detection:11501-2-AP 1:300) with L02 cells lysate 1800ug.
  • 11501-2-AP;HepG2 cells1X10^6 HepG2 cells were stained with 0.2ug ASGR2 antibody (11501-2-AP, red) and control antibody (blue). Fixed with 4% PFA blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) with dilution 1:1500.
Positive WB detected in Human liver tissue
Positive IP detected in L02 cells
Positive FC detected in HepG2 cells
Recommended dilution WB : 1:200-1:1000
IP : 1:200-1:1000
 ASGR2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen ASGR2 fusion protein ag2037 Full name Asialoglycoprotein receptor 2
Calculated molecular
weight		 39 kDa Observed molecular 
weight		 39 kDa
GenBank accession 
number		 BC017251 Gene ID (NCBI) 433
Gene symbol ASGR2 Synonyms ASGP R, ASGP R 2, ASGPR 2, ASGR2, asialoglycoprotein receptor 2, CLEC4H2, Hepatic lectin H2, HL 2, Hs.1259, L H2
Background ASGR2抗体

Asialoglycoprotein receptor (ASGPR), also known as the hepatic galactose/N-acetylglucosamine (GlcNAc) receptor or Ashwell receptor, is a C-type lectin expressed exclusively in hepatic parenchymal cells. ASGPR consists of two subunits, a major subunit (ASGR1, HL-1) and a minor subunit (ASGR2, HL-2), and specifically recognizes terminal β-linked galactose or GlcNAc on circulating glycoproteins or cells. This receptor plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins that contain terminal galactose or GlcNAc residues. ASGPR may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. ASGR2抗体

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