KIR2DL1,NK细胞抑制性受体2DL1抗体

产品编号HZ-2419R
英文名称KIR2DL1
中文名称NK细胞抑制性受体2DL1抗体
别 名Killer cell immunoglobulin-like receptor 2DL1; CD158A; Killer cell immunoglobulin like receptor 2DL1; MHC class I NK cell receptor; Natural killer associated transcript 1; NKAT 1; NKAT-1; NKAT1; p58 natural killer cell receptor clones CL-42/47.11; p58 NK receptor; p58.1 MHC class I specific NK receptor; CD158 antigen-like family member A; KI2L1_HUMAN; Natural killer-associated transcript 1; p58 NK receptor CL-42/47.11; p58.1 MHC class-I-specific NK receptor.
说 明 书0.1ml 0.2ml
研究领域免疫学
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,
KIR2DL1,NK细胞抑制性受体2DL1抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量38kDa
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human CD158a
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
KIR2DL1,NK细胞抑制性受体2DL1抗体PubMedPubMed
产品介绍background:
The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on natural killer (NK) cells and a subset of human T cells. KIR2DL1 is a receptor on human NK cells for HLA-C alleles. It inhibits the activity of NK cells thus preventing cell lysis.

Function:
Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.

Subunit:
Interacts with ARRB2. Interacts with PTPN6; the interaction is enhanced by ARRB2. Interacts with PTPN11; the interaction is enhanced by ARRB2.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the immunoglobulin superfamily.
Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

Gene ID:
3802

KIR2DL1,NK细胞抑制性受体2DL1抗体Database links:
Entrez Gene: 3802 Human
Omim: 604936 Human
SwissProt: P43626 Human
Unigene: 654605 Human
Unigene: 720721 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.