FOXO4抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
FOXO4抗体

FOXO4抗体

商家询价

产品名称： FOXO4抗体

英文名称： FOXO4Antibody

产品编号： XY19121-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 FOXO4抗体

Applications
Tested Applications: ELISA, WB, IF
Specificity Reaction: Human, Mouse; Other species are not tested.Please decide the specificity by homology
Positive WB detected in Human heart tissue, mouse heart tissue
Positive IF detected in HepG2 cells
Recommended dilution WB : 1:200-1:2000
IF : 1:10-1:100
FOXO4抗体Application key: WB=Western Blotting ,IHC=Immunohistochemistry, IF=Immunofluorescence
Images
Prev1NextView more validation data
  • 19121-1-AP;human heart tissuehuman heart tissue were subjected to SDS PAGE followed by western blot with 19121-1-AP(FOXO4 antibody) at dilution of 1:800
  • 19121-1-AP;HepG2Immunofluorescent analysis of HepG2 cells, using FOXO4 antibody 19121-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Product Information
Source: Rabbit Purify: Antigen affinity purification
IsoType: IgG Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3. -20oC, Avoid freeze / thaw cycles.
Immunogen InformationFOXO4抗体
Immunogen: Peptide Full Name: Forkhead box O4
Caculated Molecular
Weight:		 54 kDa Observed Molecular 
Weight:		 45-48kd
GenbankNo NM_005938 GeneID: 4303
Symbol FOXO4 Synonyms AFX, AFX1, forkhead box O4, Forkhead box protein O4, FOXO4, MLLT7
Background

FOXO4, also named as AFX, AFX1 and MLLT7, is a transcription factor which involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1.FOXO down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias. The antiboay can recognize isoform 1 and isoform Zeta of FOXO4.FOXO4抗体

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